Article
Integrative Model of Oxidative Stress Adaptation in the Fungal Pathogen Candida albicans.
PloS one - 1 Jan 2015
Komalapriya Chandrasekaran, Kaloriti Despoina, Tillmann Anna T, Yin Zhikang, Herrero-de-Dios Carmen, Jacobsen Mette D, Belmonte Rodrigo C, Cameron Gary, Haynes Ken, Grebogi Celso, de Moura Alessandro P S, Gow Neil A R, Thiel Marco, Quinn Janet, Brown Alistair J P, Romano M Carmen
Abstract excerpt
The major fungal pathogen of humans, Candida albicans, mounts robust responses to oxidative stress that are critical for its virulence. These responses counteract the reactive oxygen species (ROS) that are generated by host immune cells in an attempt to kill the invading fungus. Knowledge of the dynamical processes that instigate C. albicans oxidative stress responses is required for a proper understanding of...
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