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Pulmonary hypertension in children with Down syndrome

12 Feb 2020

Abstract excerpt

Individuals with Down syndrome (DS) have an increased risk of developing pulmonary hypertension (PH). In this review, we explore the epidemiology and clinical characteristics of PH in the population with DS and examine genetic, molecular and clinical contributions to the condition. The presence of an additional copy of chromosome 21 (trisomy 21) increases the risk of developing PH in children with DS through many...

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PMID: 32049444
DOI: 10.1002/ppul.24687

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