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Article

Effects of the anti-inflammatory drug celecoxib on cell death signaling in human colon cancer

2022-09-23

Abstract excerpt

The anti-inflammatory drug celecoxib, the only inhibitor of cyclooxygenase-2 (COX-2) with anticancer activity, is used to treat rheumatoid arthritis and can cause endoplasmic reticulum (ER) stress by inhibiting sarco/ER Ca 2 + -ATPase activity in cancer cells. This study aimed to investigate the correlation between celecoxib-induced ER stress and the effects of celecoxib against cell death signaling. Treatment of...

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Literature Corpus work
eca905fc-1a67-565b-9c36-0203c06e0452
DOI
10.21203/rs.3.rs-2082790/v1
Open publication

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Effects of the anti-inflammatory drug celecoxib on cell death signaling in human colon cancerDOI 10.21203/rs.3.rs-2082790/v1
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