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Drp1-mediated mitochondrial fission exacerbates inflammatory responses in intestinal epithelial cells: A potential therapeutic target for IBD

18 Aug 2025

Abstract excerpt

Inflammatory bowel disease (IBD) is a chronic inflammatory condition characterized by immune-mediated damage to the intestinal barrier. Mitochondrial fission, a crucial regulator of cellular homeostasis, has been increasingly implicated in IBD pathogenesis, although its precise role remains to be fully elucidated. This study investigated how mitochondrial fission contributes to intestinal inflammation and whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40834604
DOI: 10.1016/j.bbrc.2025.152508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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