Article

Learning gene networks under SNP perturbation using SNP and allele-specific expression data

2023-10-24

Abstract excerpt

Allele-specific expression quantification from RNA-seq reads provides opportunities to study the control of gene regulatory networks by cis -acting and trans -acting genetic variants. Many existing methods performed a single-gene and single-SNP association analysis to identify expression quantitative trait loci (eQTLs), and placed the eQTLs against known gene networks for functional interpretation. Instead, we v...

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Literature Corpus work: ec9e8e43-3c2d-5daf-860e-871bbacfac26
DOI: 10.1101/2023.10.23.563661

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