Article

Pathogenesis of Lipedema—A Regenerative Imbalance

2026-05-04

Abstract excerpt

Lipedema is a painful, chronic and progressive disorder of subcutaneous adipose tissue characterized by disproportionate, symmetrical fat accumulation in the extremities—typically the legs and less often the arms—while sparing hands and feet. It is clinically distinct from obesity and lymphoedema, affects almost exclusively women, and often exacerbates during hormonal transition phases. This paper proposes a unify...

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Literature Corpus work: ec845177-e448-5890-b328-a23621369993
DOI: 10.20944/preprints202605.0074.v1

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