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Article

A Distinct Cytokine Profile and Stromal Vascular Fraction Metabolic Status without Significant Changes in the Lipid Composition Characterizes Lipedema.

International journal of molecular sciences - 24 Mar 2021

Wolf Stefan, Deuel Jeremy W, Hollmén Maija, Felmerer Gunther, Kim Bong-Sung, Vasella Mauro, Grünherz Lisanne, Giovanoli Pietro, Lindenblatt Nicole, Gousopoulos Epameinondas

Abstract excerpt

Lipedema is an adipose tissue disorder characterized by the disproportionate increase of subcutaneous fat tissue in the lower and/or upper extremities. The underlying pathomechanism remains unclear and no molecular biomarkers to distinguish the disease exist, leading to a large number of undiagnosed and misdiagnosed patients. To unravel the distinct molecular characteristic of lipedema we performed lipidomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33805070
DOI: 10.3390/ijms22073313
PMCID: PMC8036495

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