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Article

Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis

14 Jun 2022

Abstract excerpt

Lymphedema and lipedema are complex diseases. While the external presentation of swollen legs in lower-extremity lymphedema and lipedema appear similar, current mechanistic understandings of these diseases indicate unique aspects of their underlying pathophysiology. They share certain clinical features, such as fluid (edema), fat (adipose expansion), and fibrosis (extracellular matrix remodeling). Yet, these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35743063
DOI: 10.3390/ijms23126621

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