Article

Parp3 promotes long-range end-joining in murine cells

2018-01-28

Abstract excerpt

Chromosomal rearrangements, including translocations, are early and essential events in the formation of many tumors. Previous studies that defined the genetic requirements for rearrangement formation have identified differences between murine and human cells, most notably in the role of classical‐ and alternative-nonhomologous end joining factors (NHEJ). We reported that poly(ADP)ribose polymerase 3 (PARP3) promo...

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Literature Corpus work: ec7b7df0-2a9f-5a8c-b1e1-ffcc69110eb8
DOI: 10.1101/255281

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