Article
Transgenic C. elegans as a model in Alzheimer's research.
Current Alzheimer research - 1 Jan 2005
Wu Yanjue, Luo Yuan
Abstract excerpt
Alzheimer's disease (AD) has been associated with aggregation of beta-amyloid peptide (Abeta) and cell death in the brain. Using various models, such as the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and the mouse Mus musculus, investigators have attempted to imitate the pathology process of AD for better understanding of the cellular mechanisms and for possible therapeutic...
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