Article

Modelling immune gene expression profiles as pharmacodynamic endpoints of antileishmanial treatment

2025-06-18

Abstract excerpt

<h4>Background: </h4> Cutaneous leishmaniasis (CL), a neglected infectious disease caused by the intracellular protozoan parasite Leishmania, affects over one million people annually. The type and magnitude of the inflammatory response elicited during infection leads to skin-specific immunopathology, resulting in the clinical manifestations of CL. Systemic antileishmanial drugs are the main control measure; howev...

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Literature Corpus work: ec2cae2a-d243-5efa-b229-ef27ed19fd9a
DOI: 10.22541/au.175024995.51140065/v1

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