Article

Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis

2019-12-10

Abstract excerpt

<h4>Background: </h4> Liposomal amphotericin B (AmBisome®) as a treatment modality for visceral leishmaniasis (VL) has had significant impact on patient care in some but not all regions where VL is endemic. As the mode of action of AmBisome® in vivo is poorly understood, we compared the tissue-specific transcriptome in drug-treated vs untreated mice with experimental VL. <h4>Methods: </h4>: BALB/c mice infe...

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Literature Corpus work: 829d198e-03df-5806-94c6-2f751f231172
DOI: 10.12688/wellcomeopenres.15606.1

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