Article

Mechanistic pharmacokinetic/pharmacodynamic modelling of acute inflammatory challenge models

2017-01-01

Abstract excerpt

Systemic Lupus Erythematosus (SLE), is a chronic autoimmune disease that can affect multiple organ systems. Survival rates have improved in recent years but SLE is still currently ~managed~ rather than ~cured~ and traditional treatments can cause irreversible damage, sometimes leading to death. Consequently, there is a need for new therapeutic agents that target specific components of the disease pathogenesis. Thi...

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Literature Corpus work: 2919c5eb-7b9d-5f46-9848-37b18bebfb88
DOI: 10.48730/wfav-2h90

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