Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing

20 Oct 2021

Abstract excerpt

infection process, we both validated our work and found eight drugs already approved for use in humans that to the best of our knowledge were never employed to treat leishmaniasis, rendering our work as a new tool in the box available to the scientific community fighting parasites.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34668739
DOI: 10.1128/spectrum.01018-21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug RepurposingPMID 34668739Read ↗

Network-driven analysis of human–Plasmodium falciparum interactome: processes for malaria drug discovery and extracting in silico targetsSemantic proximity Read ↗

Designing a Network Proximity-Based Drug Repurposing Strategy for COVID-19Semantic proximity Read ↗

Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical diseaseSemantic proximity Read ↗

Emerging therapeutic targets for treatment of leishmaniasisSemantic proximity Read ↗

Host-Directed Therapies for Parasitic DiseasesSemantic proximity Read ↗

Network-Based Identification and Experimental Validation of Drug Candidates Toward SARS-CoV-2 via Targeting Virus–Host InteractomeSemantic proximity Read ↗

A connectivity map-based drug repurposing study and integrative analysis of transcriptomic profiling of SARS-CoV-2 infectionSemantic proximity Read ↗

Malaria Parasite Metabolic Pathways (MPMP) Upgraded with Targeted Chemical CompoundsSemantic proximity Read ↗

Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug ResistanceSemantic proximity Read ↗

A Data-Driven Approach to Construct a Molecular Map of Trypanosoma cruzi to Identify Drugs and Vaccine TargetsSemantic proximity Read ↗

Connecting the dots: applications of network medicine in pharmacology and disease.Semantic proximity Read ↗

Potential therapeutic targets and the role of technology in developing novel antileishmanial drugs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.