Article

Molecular and biochemical pharmacology of mitochondrial enzymes in the malaria parasite Plasmodium falciparum

2011-01-01

Abstract excerpt

The mitochondria of malaria have big potential to be explored as a drug targeting site. This is due to the differences in the composition of the Plasmodium respiratory complex compared with the human host. The Plasmodium respiratory chain consists of 2 unique dehydrogenases PfNDH2 and MQO which are only encoded in prokaryotic cells. Apart from these two, thy Plasmodium bc1 complex has low amino acid similarity whe...

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Literature Corpus work: ec04fef1-5398-5907-9073-71bb8af7fc06
DOI: 10.17638/03062882

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