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<i>Plasmodium falciparum</i> mitochondrial complex III, the target of atovaquone, is essential for progression to the transmissible sexual stages

2024-01-09

Abstract excerpt

The Plasmodium mitochondrial electron transport chain (mETC) is responsible for essential metabolic pathways such as de novo pyrimidine synthesis and ATP synthesis. The mETC complex III (cytochrome bc1 complex) is responsible for transferring electrons from ubiquinol to cytochrome c and generating a proton gradient across the inner mitochondrial membrane, which is necessary for the function of ATP synthase. Recent...

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Literature Corpus work
66e4d563-c1c1-543e-8b21-61f4b056c126
DOI
10.1101/2024.01.09.574740
Open publication

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<i>Plasmodium falciparum</i> mitochondrial complex III, the target of atovaquone, is essential for progression to the transmissible sexual stagesDOI 10.1101/2024.01.09.574740
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