Article

Meta-analysis of metagenomes via machine learning and assembly graphs reveals strain switches in Crohn’s disease

2022-07-05

Abstract excerpt

Microbial strains have closely related genomes but may have different phenotypes in the same environment. Shotgun metagenomic sequencing can capture the genomes of all strains present in a community but strain-resolved analysis from shotgun sequencing alone remains difficult. We developed an approach to identify and interrogate strain-level differences in groups of metagenomes. We use this approach to perform a me...

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Literature Corpus work: ebf10f58-13f4-5c41-9352-55403f1ed6be
DOI: 10.1101/2022.06.30.498290

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Meta-analysis of metagenomes via machine learning and assembly graphs reveals strain switches in Crohn’s diseaseDOI 10.1101/2022.06.30.498290Read

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