Article

Scalable microbial strain inference in metagenomic data using StrainFacts

2022-02-04

Abstract excerpt

While genome databases are nearing a complete catalog of species commonly inhabiting the human gut, their representation of intraspecific diversity is lacking for all but the most abundant and frequently studied taxa. Statistical deconvolution of allele frequencies from shotgun metagenomic data into strain genotypes and relative abundances is a promising approach, but existing methods are limited by computational...

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Literature Corpus work: 3ad41ffe-d581-5690-bee8-652ab49c7b1b
DOI: 10.1101/2022.02.01.478746

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