Article

Improved detection of microbiome-disease associations via population structure-aware generalized linear mixed effects models (microSLAM)

2024-06-30

Abstract excerpt

Microbiome association studies typically link host disease or other traits to summary statistics measured in metagenomics data, such as diversity or taxonomic composition. But identifying disease-associated species based on their relative abundance does not provide insight into why these microbes act as disease markers, and it overlooks cases where disease risk is related to specific strains with unique biological...

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Literature Corpus work: 91c1bae1-7e7a-5dbd-a8b9-a3b2c5119fd7
DOI: 10.1101/2024.06.27.600934

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