Article

Chromatin remodeler Chd7 regulates photoreceptor development and outer segment length

2022-05-30

Abstract excerpt

Mutations in the chromatin remodeling factor CHD7 are the predominant cause of CHARGE syndrome, a congenital disorder that frequently includes ocular coloboma. Although CHD7 is known to be required for proper ocular morphogenesis, its role in retinal development has not been thoroughly investigated. Given that individuals with CHARGE syndrome can experience visual impairment even in the absence of coloboma, a bett...

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Literature Corpus work: eb9426d3-838c-5e90-8d50-d02e3b65dee8
DOI: 10.1101/2022.05.30.494019

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