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Article

Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome.

Developmental biology - 1 Oct 2013

Balow Stephanie A, Pierce Lain X, Zentner Gabriel E, Conrad Patricia A, Davis Stephani, Sabaawy Hatem E, McDermott Brian M, Scacheri Peter C

Abstract excerpt

CHARGE syndrome is a sporadic autosomal-dominant genetic disorder characterized by a complex array of birth defects so named for its cardinal features of ocular coloboma, heart defects, choanal atresia, growth retardation, genital abnormalities, and ear abnormalities. Approximately two-thirds of...

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Source

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Identifiers

PMID: 23920116
DOI: 10.1016/j.ydbio.2013.07.026
PMCID: PMC3816111

Genes

CHD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23920116-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome.PMID 23920116Read ↗

Multi-omic analyses identify molecular targets of Chd7 that contribute to CHARGE syndrome model phenotypes.Semantic proximity Read ↗

Multi-omic analyses identify molecular targets of Chd7 that mediate CHARGE syndrome model phenotypesSemantic proximity Read ↗

CHD7 regulates craniofacial cartilage development via controlling HTR2B expressionSemantic proximity Read ↗

Chromodomain proteins in development: lessons from CHARGE syndromeSemantic proximity Read ↗

The chromatin remodeling protein CHD7, mutated in CHARGE syndrome, is necessary for proper craniofacial and tracheal developmentSemantic proximity Read ↗

Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues.Semantic proximity Read ↗

Analysis of CHD-7 defective dauer nematodes implicates collagen misregulation in CHARGE syndrome featuresSemantic proximity Read ↗

Clinical and molecular effects of CHD7 in the heart.Semantic proximity Read ↗

Spectrum of CHD7 mutations in 110 individuals with CHARGE syndrome and genotype-phenotype correlation.Semantic proximity Read ↗

CHD7 regulates cardiovascular development through ATP-dependent and -independent activities.Semantic proximity Read ↗

Discovery of a novel CHD7 CHARGE syndrome variant by integrated omics analyses.Semantic proximity Read ↗

Role of Chd7 in Zebrafish: A Model for CHARGE SyndromeSemantic proximity Read ↗

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