Article

Transcriptome analysis of the zebrafish <i>atoh7−/−</i> mutant, <i>lakritz</i> , highlights Atoh7-dependent genetic networks with potential implications for human eye diseases

2020-04-10

Abstract excerpt

<h4>ABSTRACT</h4> Expression of the bHLH transcription protein Atoh7 is a crucial factor conferring competence to retinal progenitor cells for the development of retinal ganglion cells. A number of studies have emerged establishing ATOH7 as a retinal disease gene. Remarkably, such studies uncovered ATOH7 variants associated with global eye defects including optic nerve hypoplasia, microphthalmia, retinal vascul...

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Literature Corpus work: 62244c06-2e2e-536c-867e-049acfe998d7
DOI: 10.1101/2020.04.09.033704

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