Article

Q-STARZ: Quantitative Spatial and Temporal Assessment of Regulatory element activity in Zebrafish

2020-09-14

Abstract excerpt

<h4>ABSTRACT</h4> Noncoding regions of the genome harbouring cis-regulatory elements (CREs) or enhancers drive spatial and temporal gene expression. Mutations or single nucleotide polymorphisms (SNPs) in enhancers have been widely implicated in human diseases and disease-predispositions. However, our ability to assay the regulatory potential of genetic variants in enhancers is currently very limited, in part beca...

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Literature Corpus work: eb8d8333-54c5-5d39-997c-2a90b259f5de
DOI: 10.1101/2020.09.13.290460

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