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Development of a Diagnostic Model for Barrett's Esophagus and Esophageal Adenocarcinoma Based on Machine Learning and Immune Infiltration

2025-12-03

Abstract excerpt

<title>Abstract</title> <p>Background Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with Barrett's esophagus (BE) as its only known precursor. Early diagnosis is challenging, and the key biomarkers and mechanisms driving the BE-to-EAC progression are not fully understood. Methods We integrated transcriptomic data from BE (from the Gene Expression Omnibus (GEO)) and EAC (from The Cancer Genome Atlas (...

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Literature Corpus work
289c4a05-6b42-5760-a171-ae88332380f0
DOI
10.21203/rs.3.rs-8004374/v1
Open publication

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Development of a Diagnostic Model for Barrett's Esophagus and Esophageal Adenocarcinoma Based on Machine Learning and Immune InfiltrationDOI 10.21203/rs.3.rs-8004374/v1
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