Article

Increased expression of genetically-regulated <i>FLT3</i> implicated in Tourette’s Syndrome

2019-10-21

Abstract excerpt

Tourette’s Syndrome (TS) is a neurodevelopmental disorder that is characterized by motor and phonic tics. A recent TS genome-wide association study (GWAS) identified a genome-wide significant locus. However, determining the biological mechanism of GWAS signals remains difficult. Here, we conduct a TS transcriptome-wide association study (TWAS) consisting of 4,819 cases and 9,488 controls and found that increased e...

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Literature Corpus work: eb8a2197-c1ea-503a-b75e-80bf480a2d63
DOI: 10.1101/812420

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