Article

Systematic Transmission Electron Microscopy-Based Identification and 3D Reconstruction of Cellular Degradation Machinery

2021-09-27

Abstract excerpt

Many interconnected degradation machineries including autophagosomes, lysosomes, and endosomes work in tandem to conduct autophagy, an intracellular degradation system that is crucial for cellular homeostasis. Altered autophagy contributes to the pathophysiology of various diseases, including cancers and metabolic diseases. Although many studies have investigated autophagy to elucidate disease pathogenesis, identi...

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Literature Corpus work: eb5c6f55-1560-5c7e-99ae-ce9cc39e4291
DOI: 10.1101/2021.09.26.461841

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