Article

Systems biology analysis identifies TCF7L1 as a key regulator of metastasis in Ewing sarcoma

2021-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Identification of cancer stemness genes is crucial to understanding the underlying biology of therapy resistance, relapse, and metastasis. Ewing sarcoma (EwS) is the second most common bone tumor in children and adolescents. It is a highly aggressive cancer associated with a dismal survival rate (<30%) for patients with metastatic disease at diagnosis (∼25% of cases). Hence, deciphering the unde...

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Literature Corpus work: eb3e6833-c44c-52fa-b935-962f9276ef43
DOI: 10.1101/2021.02.25.432862

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