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Multi-Omics Mendelian Randomization Integrating GWAS, eQTL, RNA-seq and Cell Line Experiment Reveal GLIPR1 and ARHGAP11A as Potential Targets of EGCG for Nasopharyngeal Carcinoma

2025-07-16

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<title>Abstract</title> <p> <bold>Background:</bold> Epigallocatechin gallate (EGCG), a frequently studied catechin in green tea, has been shown to be involved in the antiproliferation and apoptosis of human Nasopharyngeal carcinoma (NPC) cells. Therefore, we aimed to find the drug targets that improve the prognosis of NPC. <bold>Methods:</bold> NPC cell line experiments, high-throughput sequencing, Mendelian...

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Literature Corpus work
eb2ecac9-9b39-5656-bb74-9e6b7ed45a5f
DOI
10.21203/rs.3.rs-6957738/v1
Open publication

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Multi-Omics Mendelian Randomization Integrating GWAS, eQTL, RNA-seq and Cell Line Experiment Reveal GLIPR1 and ARHGAP11A as Potential Targets of EGCG for Nasopharyngeal CarcinomaDOI 10.21203/rs.3.rs-6957738/v1
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