Article

Maternal Risk for Down Syndrome Is Modulated by Genes Involved in Folate Metabolism

2012-01-01

Abstract excerpt

Studies have shown that the maternal risk for Down syndrome (DS) may be modulated by alterations in folate metabolism. The aim of this study was to evaluate the influence of 12 genetic polymorphisms involved in folate metabolism on maternal risk for DS. In addition, we evaluated the impact of these polymorphisms on serum folate and plasma methylmalonic acid (MMA, an indicator of vitamin B 12 status) concentrations...

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Literature Corpus work: eb0a8259-4da4-552a-84fb-0278413a8d30
DOI: 10.1155/2012/693864

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