Article
Opposing Roles of the Fork-head box genes FoxM1 and FoxA2 in Hepatocellular Carcinoma
2018-08-02
Abstract excerpt
<h4>ABSTRACT</h4> The fork-head box transcription factor FoxMl is essential for hepatocellular carcinoma (HCC) development and its overexpression coincides with poor prognosis. Here, we show that the mechanisms by which FoxM1 drives HCC progression involve overcoming the inhibitory effects of the liver differentiation gene FoxA2. First, the expression patterns of FoxM1 and FoxA2 in human HCC are opposite. We show...
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Identifiers and source
- Literature Corpus work
- eaf252ac-2b8b-55af-972a-cf2286a58d6a
- DOI
- 10.1101/383604