Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Forkhead Box Transcription Factors: Double-Edged Swords in Cancer

22 Mar 2022

Abstract excerpt

A plethora of treatment options exist for cancer therapeutics, but many are limited by side effects and either intrinsic or acquired resistance. The need for more effective targeted cancer treatment has led to the focus on forkhead box (FOX) transcription factors as possible drug targets. Forkhead factors such as FOXA1 and FOXM1 are involved in hormone regulation, immune system modulation, and disease progression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to FOXO transcription factor regulation
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35315926
DOI: 10.1158/0008-5472.can-21-3371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Forkhead Box Transcription Factors: Double-Edged Swords in CancerPMID 35315926Read ↗

The Dominant Role of Forkhead Box Proteins in CancerSemantic proximity Read ↗

FOXM1 and Cancer: Faulty Cellular Signaling Derails HomeostasisSemantic proximity Read ↗

A New Fork for Clinical Application: Targeting Forkhead Transcription Factors in CancerSemantic proximity Read ↗

The forkhead-box family of transcription factors: key molecular players in colorectal cancer pathogenesisSemantic proximity Read ↗

Role of Forkhead Box Class O proteins in cancer progression and metastasisSemantic proximity Read ↗

Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and drug resistanceSemantic proximity Read ↗

FOXK2 Transcription Factor and Its Emerging Roles in CancerSemantic proximity Read ↗

Deciphering the roles of FOXO1 in human neoplasmsSemantic proximity Read ↗

Role and regulation of FOXO3a: new insights into breast cancer therapySemantic proximity Read ↗

FOXO transcription factors in cancer development and therapy.Semantic proximity Read ↗

FOXA1 and FOXA2: the regulatory mechanisms and therapeutic implications in cancerSemantic proximity Read ↗

Clever cancer strategies with FoxO transcription factorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.