Article
FOX transcription factor family in hepatocellular carcinoma.
Biochimica et biophysica acta. Reviews on cancer - 1 Aug 2020
Gong Zhongqin, Yu Jianqing, Yang Shucai, Lai Paul B S, Chen George G
Abstract excerpt
The pathogenesis of hepatocellular carcinoma (HCC) is a multistep process, involving the progressive accumulation of molecular alterations and transcriptomic alterations. The Forkhead-box (FOX) transcription factor family is characterized by its unique DNA binding domain (FKH or winged-helix domain). Human FOX family consists of about 17 subfamilies, at least 43 members. Some of them are liver-enriched...
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