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Dissecting gonadal cell lineage specification and sex determination during human development using a single-cell transcriptomics approach

2020-11-11

Abstract excerpt

<title>Abstract</title> <p>Gonadal somatic cells are the main players in gonad development and are important for sex determination and germ cell development. Here, using a time-series scRNA-seq strategy, we analyzed the fetal germ cells (FGCs) and gonadal somatic cells in human embryos and fetuses. Clustering analysis of testes and ovaries revealed several novel cell subsets, including <italic>POU5F1</italic><sup...

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Literature Corpus work
8931593b-5b0a-5e71-a4fa-5d0de62e1d99
DOI
10.21203/rs.3.rs-88057/v1
Open publication

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Dissecting gonadal cell lineage specification and sex determination during human development using a single-cell transcriptomics approachDOI 10.21203/rs.3.rs-88057/v1
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