Article
Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humans
2023-08-08
Abstract excerpt
Gonad development is an exciting model to study cell fate commitment. However, the specification and differentiation of somatic cell lineages within the testis and the ovary are incompletely characterized, especially in humans. In fact, a better understanding of sex determination first requires the identification of all the cell types involved and of their dynamic expression programs. Here we present a comprehensi...
Topics
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- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Prenatal Screening and Diagnostics
- Renal and related cancers
- Reproductive Biology and Fertility
- Sexual Differentiation and Disorders
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- 377fe113-0e08-5a55-af0d-691b67fd0cd4
- DOI
- 10.1101/2023.08.07.552336
