Article

Robust Harmonization of Microbiome Studies by Phylogenetic Scaffolding with MaLiAmPi

2022-07-27

Abstract excerpt

Microbiome science is difficult to translate back to patients due to an inability to harmonize 16S rRNA gene-based microbiome data, as differences in the technique will result in different amplicon sequence variants (ASV) from the same microbe. Here we demonstrate that placement of ASV onto a common phylogenetic tree of full-length 16S rRNA alleles can harmonize microbiome studies. Using in silico data approxim...

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Literature Corpus work: eae4e735-180b-5805-a453-bc7709f580d2
DOI: 10.1101/2022.07.26.501561

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