Article

Guide scaffolding improves phylogenetic accuracy and enables integration across 16S amplicon regions

2026-01-06

Abstract excerpt

<h4>ABSTRACT</h4> The growing magnitude and scale of microbiome studies now support application of meta-analytical frameworks, however the challenge of integrating microbiome sequence data across distinct studies into a unified phylogeny remains a critical barrier to progress. The 16S rDNA gene has been key to sequence-based phylogenetic microbial community analyses for over 30 years in applications ranging from...

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Literature Corpus work: f95be18d-c549-5799-8830-69cf3d57ec4c
DOI: 10.64898/2026.01.05.697767

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