Article
Alignment and clustering of phylogenetic markers--implications for microbial diversity studies.
BMC bioinformatics - 24 Mar 2010
White James R, Navlakha Saket, Nagarajan Niranjan, Ghodsi Mohammad-Reza, Kingsford Carl, Pop Mihai
Abstract excerpt
BACKGROUND: Molecular studies of microbial diversity have provided many insights into the bacterial communities inhabiting the human body and the environment. A common first step in such studies is a survey of conserved marker genes (primarily 16S rRNA) to characterize the taxonomic composition a...
Topics
- Cluster Analysis
- DNA, Bacterial
- Genetic Markers
- Genetic Variation
- Phylogeny
- RNA, Bacterial
- RNA, Ribosomal, 16S
- Sequence Alignment
