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Article

Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies

4 Feb 2016

Abstract excerpt

Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants identified MN-associated loci at HLA-DQA1 and PLA2R1. Methods: We used a combined approach of genotype imputation, GWAS, human leucocyte antigen (HLA) imputation and extension to other aetiologies of chronic kidney disease (CKD) to investigate...

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PMID: 27333618
DOI: 10.1093/ndt/gfw001

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