Article

Carbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome

2024-05-21

Abstract excerpt

<h4>Background</h4> Approximately one in every 800 children is born with the severe aneuploid condition of Down Syndrome (DS), a trisomy of chromosome 21. Low blood pressure (hypotension) is a common condition associated with DS and can have a significant impact on exercise tolerance and quality of life. Little is known about the factors driving this hypotensive phenotype and therefore therapeutic interventions a...

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Literature Corpus work: eac901dd-5bef-5678-a150-82fab5cc1a57
DOI: 10.1101/2024.05.17.594787

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