Article

STAR Suite: Transcriptomics processing in a single binary through AI-assisted development

2026-03-10

Abstract excerpt

Single-cell transcriptomic assays—pooled CRISPR/Perturb-seq screens, clonal lineage tracing, and 10x Flex fixed RNA profiling—are central to modern biology, yet their processing has depended on Cell Ranger, a proprietary tool restricted to 10x products, with no open end-to-end pipeline for Perturb-seq or Flex. We present STAR Suite, which extends the STAR aligner into a single executable that processes bulk RNA-se...

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Literature Corpus work: eaa198a2-2f0a-5ba5-bd24-bb30ba4efad2
DOI: 10.64898/2026.03.09.710580

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