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Associations between<i>CYP3A4, CYP3A5</i>and<i>SCN1A</i>Polymorphisms and Carbamazepine Metabolism in Epilepsy: A Meta-analysis

2020-03-06

Abstract excerpt

<h4>Background and objective</h4> CYP3A4 (rs2242480), CYP3A5 (rs776746) and SCN1A (rs3812718 and rs2298771) gene polymorphisms were previously indicated to be associated with carbamazepine (CBZ) metabolism and resistance in epilepsy. However, previous studies regarding the effects of these polymorphisms still remain controversial. Therefore, we performed a meta-analysis to evaluate whether the four polymorphisms a...

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Literature Corpus work
ea9c1566-ae60-51a4-ae99-5ecf86d08e2d
DOI
10.1101/2020.03.03.20030783
Open publication

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Associations between<i>CYP3A4, CYP3A5</i>and<i>SCN1A</i>Polymorphisms and Carbamazepine Metabolism in Epilepsy: A Meta-analysisDOI 10.1101/2020.03.03.20030783
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