Article

Molecular counting enables accurate and precise quantification of methylated ctDNA for tumor-naive cancer therapy response monitoring

2023-06-04

Abstract excerpt

Personalized cancer treatment can significantly extend survival and improve quality of life for many patients, but accurate and real-time therapy response monitoring remains challenging. To overcome logistical and technical challenges associated with using imaging scans or assays that track the variant allele fraction (VAF) of somatic mutations in circulating tumor DNA (ctDNA) for response monitoring, we developed...

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Literature Corpus work: ea8fc52b-58ad-5f93-94a3-9309cedf5862
DOI: 10.1101/2023.05.31.23290555

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