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Methylated circulating tumor DNA in blood: power in cancer prognosis and response

13 Jan 2016

Abstract excerpt

Circulating tumor DNA (ctDNA) in the plasma or serum of cancer patients provides an opportunity for non-invasive sampling of tumor DNA. This 'liquid biopsy' allows for interrogations of DNA such as quantity, chromosomal alterations, sequence mutations and epigenetic changes, and can be used to guide and improve treatment throughout the course of the disease. This tremendous potential for real-time 'tracking' in a...

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PMID: 26764421
DOI: 10.1530/erc-15-0369

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