Article

Systematic benchmarking of multi-modal approaches for tumor-naïve ctDNA detection and quantification

2026-06-24

Abstract excerpt

Longitudinal monitoring of circulating tumor DNA (ctDNA) has emerged as a promising framework for characterizing treatment response dynamics in cancer. Scalable tumor-naïve approaches for quantifying ctDNA often involve whole-genome sequencing (WGS) or DNA methylation profiling, but their comparative performance and capacity for complementary integration remain poorly understood. Here we systematically benchmarked...

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Literature Corpus work: 278e78bc-db81-5f20-8f40-ee3d030a9a29
DOI: 10.64898/2026.06.19.733293

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