Article

Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice

2020-10-23

Abstract excerpt

Goblet cells (GCs) are specialized cells of the intestinal epithelium contributing critically to mucosal homeostasis. One of the functions of GCs is to produce and secrete MUC2, the mucin that forms the scaffold of the intestinal mucus layer coating the epithelium and separates the luminal pathogens and commensal microbiota from the host tissues. Although a variety of ion channels and transporters are thought to i...

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Identifiers and source

Literature Corpus work: ea87e655-e3ef-5c60-a2de-808223511606
DOI: 10.1101/2020.10.23.341396

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