Article

Separating the signal from the noise in metagenomic cell-free DNA sequencing

2020-01-22

Abstract excerpt

<title>Abstract</title> <p>Background: Cell-free DNA (cfDNA) in blood, urine and other biofluids provides a unique window into human health. A proportion of cfDNA is derived from bacteria and viruses, creating opportunities for the diagnosis of infection via metagenomic sequencing. The total biomass of microbial-derived cfDNA in clinical isolates is low, which makes metagenomic cfDNA sequencing susceptible to con...

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Literature Corpus work: ea813490-6f2e-5b4c-af12-ec62266bd0db
DOI: 10.21203/rs.2.17385/v2

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