Article

A comprehensive single-cell atlas of freshly-dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective fresh synovial biopsy collection

2022-06-22

Abstract excerpt

<title>Abstract</title> <p>Single-cell RNA-sequencing is advancing our understanding of synovial pathobiology in inflammatory arthritis. Here, we optimized the protocol for dissociation of synovial biopsies and created a comprehensive reference single-cell atlas of fresh human synovium in inflammatory arthritis. We derived our protocol from the published dissociation method for cryopreserved synovium (Donlin L. e...

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Literature Corpus work: ea7da47e-8b21-51b8-97be-50e3db2e27e7
DOI: 10.21203/rs.3.rs-1702574/v1

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