Back to search

Article

High dimensional analyses of cells dissociated from cryopreserved synovial tissue

2018-03-19

Abstract excerpt

<h4>Background</h4> Detailed molecular analyses of cells from rheumatoid arthritis (RA) synovium hold promise in identifying cellular phenotypes that drive tissue pathology and joint damage. The Accelerating Medicines Partnership (AMP) RA/SLE network aims to deconstruct autoimmune pathology by examining cells within target tissues through multiple high-dimensional assays. Robust standardized protocols need to be...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
41e556a4-c598-5eeb-ab80-f058496a72c2
DOI
10.1101/284844
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
High dimensional analyses of cells dissociated from cryopreserved synovial tissueDOI 10.1101/284844
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissueSemantic proximity
A comprehensive single-cell atlas of freshly-dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective fresh synovial biopsy collectionSemantic proximity
A reference single-cell map of freshly dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective synovial biopsy collectionSemantic proximity
Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritisSemantic proximity
Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low cost microfluidic instrumentationSemantic proximity
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.Semantic proximity
Integrative Spatial Proteomics and Single-Cell RNA Sequencing Unveil Molecular Complexity in Rheumatoid Arthritis for Novel Therapeutic TargetingSemantic proximity
Synovial Transcriptome Profiling for Predicting Biological Treatment Response in Rheumatoid Arthritis: A Feasibility studySemantic proximity
Single Cell Transcriptomics and Flow Cytometry Reveal Disease-associated Fibroblast Subsets in Rheumatoid ArthritisSemantic proximity
Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentationSemantic proximity
A protocol for single-cell transcriptomics from cryopreserved renal tissue and urine for the Accelerating Medicine Partnership (AMP) RA/SLE networkSemantic proximity
Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencingSemantic proximity
Select a neighboring publication to make it the new centre.