Article

Human Fibroblast-Myeloid cell tissue atlas across lung, synovium, skin and heart

2025-03-04

Abstract excerpt

Single-cell RNA sequencing (scRNAseq) of human tissues has expanded our understanding of the complexity of cellular subsets and their changes in disease. The availability of scRNAseq data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue-specific myeloid and stroma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3c1cffc7-11bb-5fd1-ab87-fe29f6cd0f8a
DOI: 10.1101/2025.03.04.641204

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human Fibroblast-Myeloid cell tissue atlas across lung, synovium, skin and heartDOI 10.1101/2025.03.04.641204Read

A consensus single-cell transcriptomic atlas of dermal fibroblast heterogeneitySemantic proximity Read

Single-cell transcriptome profiling of an adult human cell atlas of 15 major organsSemantic proximity Read

A reference single-cell map of freshly dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective synovial biopsy collectionSemantic proximity Read

Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulationSemantic proximity Read

Single-cell transcriptome profiling of an adult human cell atlas of 15 major organsSemantic proximity Read

Cross-tissue single-cell transcriptomics reveals organizing principles of fibroblasts in health and diseaseSemantic proximity Read

Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritisSemantic proximity Read

Stromal heterogeneity in the adult lung delineated by single-cell genomicsSemantic proximity Read

Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseasesSemantic proximity Read

Integrative single cell analysis to decode transcriptomic heterogeneity in pulmonary fibrosis across diverse pathologiesSemantic proximity Read

A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populationsSemantic proximity Read

A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lungSemantic proximity Read