Article

Optimal Haplotype Assembly from High-Throughput Mate-Pair Reads

2015-02-07

Abstract excerpt

Humans have $23$ pairs of homologous chromosomes. The homologous pairs are almost identical pairs of chromosomes. For the most part, differences in homologous chromosome occur at certain documented positions called single nucleotide polymorphisms (SNPs).A haplotype of an individual is the pair of sequences of SNPs on the two homologous chromosomes. In this paper, we study the problem of inferring haplotypes of ind...

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Literature Corpus work: ea7cd5a8-73ab-50f6-b653-65ddd6e4c45b
DOI: 10.1101/014993

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